Reply.io is a sales engagement platform that combines multichannel sequences, email outreach, LinkedIn automation, calling, and an AI SDR agent (Jason AI) to automate B2B outbound. It supports multi-step sequences, A/B testing, reply detection, out-of-office handling, and AI-generated message variations. Plans are tiered around email volume, multichannel outreach, and AI SDR automation.
⚡ Email Marketing💵 Paid — plans start at $49/user/mo (Email Volume), $89/user/mo (Multichannel), and an Agency white-label plan from $166/mo; annual billing saves 20-30%.📅 Listed 10 Jun 2026
✨ Features
Jason AI SDR
An AI agent trained for B2B outreach handles prospecting, personalization, follow-ups, and replies.
Multichannel Sequences
Combine email, LinkedIn, and calling steps into automated outbound sequences.
Reply Detection and OOO Handling
AI detects replies and out-of-office messages to keep sequences accurate.
A/B Testing and AI Variations
Test message variants and auto-generate AI-written variations to lift reply rates.
⚖️ Pros & Cons
Pros
✓ Strong multichannel automation across email, LinkedIn, and calling
✓ Built-in AI SDR agent automates outbound
✓ Annual billing offers meaningful savings
Cons
✗ Real cost rises with add-ons (LinkedIn, calling, enrichment)
✗ Per-seat pricing gets expensive for larger teams